Expression of myelomonocytic antigens on chronic lymphocytic leukemia B cells.
نویسندگان
چکیده
We analyzed the expression of myelomonocytic-associated antigens on lymphocytes from B cell chronic lymphocytic leukemia (B-Cu) patients. Blood mononuclear cells were depleted of monocytes by one-step Percoll density gradient centrifugation and tested for antigen expression by fluorescent microscopy and flow cytometry. The reactivity of patient lymphocytes was as follows: 26 of 31 were positive for CD14 (Myr). 22 of 31 for a monocyte Fc receptor (MFC-1 ). 22 of 31 for CD1 1 b (C3bi receptor). eight of 31 for CD15 (Leu-M1). five of 18 for CD13 (My 7). seven of 18 for My 9. and five of 30 for Mo 2. The B lymphocytes of B-Cu patients were also tested for the ability to produce interleukin 1 (IL-i ) after depletion of
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عنوان ژورنال:
- Blood
دوره 72 4 شماره
صفحات -
تاریخ انتشار 1988